![]() Because of the extended use of aspirin and the urge of its stopping for the above mentioned reasons, the occurrence of a prothrombotic effect after the discontinuation of aspirin therapy may play an important role in recurrence of ischemic cerebrovascular disease. ![]() Many situations are associated with the discontinuation of aspirin: before surgical interventions, hemorrhagic disorders, interactions with other drugs, the patient’s negligence, dementia, and drug intolerance. It can cause a reduction in ischemic stroke of about 25% in high-risk patients. Īspirin is the cornerstone of secondary stroke prevention. In other studies, the frequency of prior ischemic stroke in patients with acute ischemic stroke is about 11–25%. The recurrence rate of ischemic stroke was reported to be 40% after 5 years of follow-up. The incidence of ischemic cerebrovascular strokes and transient ischemic attacks was about 5. Physicians need to educate patients about the importance of adherence of aspirin therapy. Conclusionĭiscontinuation of aspirin especially for a period of 8–30 days could increase the risk of recurrent ischemic stroke in patients with very high-risk and high-risk factors. Very high-risk patients were associated with stroke in 8–30 days of discontinuation, high-risk patients were associated with stroke in 181–365 days of discontinuation while moderate-risk patients were associated with stroke in 31–180 days of discontinuation. Nearly half of the patients (25/53) discontinue aspirin for 8–30 days before a stroke. We found that 51% of patients discontinue aspirin compared to 28.8% of the control group. Investigations included brain CT or brain MRI for all patients, and the site of infarction was classified according to the Oxford classification. The following information was collected: history of aspirin discontinuation and cause and time of discontinuation. Both sexes were included with age over 18 years. This is a descriptive case–control study, including 104 patients with recurrent ischemic stroke and 104 controls. Study the effect of aspirin discontinuation in recurrence of ischemic cerebrovascular stroke. The study included 125,505 people, with 10,590 self-reporting a history of cardiovascular disease.Discontinuation of aspirin was suggested to be a risk factor for recurrent ischemic stroke however, it was underestimated by most physicians. The surveys included questions about people’s medical history of cardiovascular disease and on aspirin use. The researchers analyzed data from nationally representative health surveys in 51 countries. Contributing factors include smoking, diabetes, unhealthy diet, genetics, lack of exercise, obesity and air pollution. The study notes that cardiovascular disease, including heart attack and stroke, is the world’s leading cause of death. Such blockage also can cause other complications, including a heart attack or stroke. These clots can block arteries and contribute to a reduction in the amount of oxygen-rich blood being delivered to vital organs. The study didn’t explain those figures, but Yoo said likely reasons include varying access to health care, inconsistent messaging surrounding use of the drug, and the fact that aspirin is a prescription drug in some countries.Īspirin is a blood thinner, preventing small blood cells called platelets from forming clots.
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